The intravenous model of murine tuberculosis is less pathogenic than the aerogenic model owing to a more rapid induction of systemic immunity

P. J. Cardona, A. Cooper, M. Luquín, A. Ariza, F. Filipo, I. M. Orme, V. Ausina

Producción científica: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

56 Citas (Scopus)

Resumen

The detection of mRNA in the murine model of tuberculosis for key cytokines involved in protective immunity in the lung tissues revealed a much faster emergence of the interferon (IFN)-γ response in the intravenous route than in the aerosol route of inoculation. This slower response in the lungs was associated with a stronger inflammatory response, resulting in large granulomatous structures and eventual tissue damage.
Idioma originalInglés
Páginas (desde-hasta)362-366
PublicaciónScandinavian Journal of Immunology
Volumen49
DOI
EstadoPublicada - 28 abr 1999

Huella

Profundice en los temas de investigación de 'The intravenous model of murine tuberculosis is less pathogenic than the aerogenic model owing to a more rapid induction of systemic immunity'. En conjunto forman una huella única.

Citar esto