The ALPIM (Anxiety, laxity, pain, immune, and mood) syndrome in adolescents and young adults: A cohort study

Deepan Singh, Wendy Rocio Martinez, Niyati Anand, Aaron Pinkhasov, Rose Calixte, Antonio Bulbena, Jeremy D. Coplan

Producción científica: Contribución a una revistaArtículoInvestigación

2 Citas (Scopus)

Resumen

Objective: ALPIM (anxiety, laxity, pain, immune, and mood) syndrome has been previously described in adults. The authors aimed to identify its occurrence in adolescents and confirm its existence in adults. Given the association of the disorder with somatic symptoms, separation anxiety disorder (SAD) was explored as an ALPIM comorbidity. Methods: Medical records of patients aged 11–34 with a diagnosis of depression or anxiety (panic disorder, SAD, social anxiety or generalized anxiety disorder) seen during a 1-year period were reviewed. Data were collected on the presence of ALPIM comorbidities. Analyses were conducted to detect their co-occurrence and evaluate possible predictors of the ALPIM syndrome. Results: Inclusion criteria were met by 185 patient charts. A significant association was observed between the ALPIM comorbidities with 20 study subjects (10.8%) meeting criteria for ALPIM syndrome (patients with one or more diagnoses from each ALPIM domain). Patients with SAD had increased odds of being diagnosed with ALPIM (odds ratio=7.14, 95% CI=2.48–20.54, p
Idioma originalInglés
Páginas (desde-hasta)239-245
PublicaciónJournal of Neuropsychiatry and Clinical Neurosciences
Volumen31
DOI
EstadoPublicada - 1 jul 2019

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