Spatial fractionation of the dose using neon and heavier ions: A Monte Carlo study.

C Peucelle, I Martínez-Rovira, Y Prezado

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Resumen

This work explores a new radiation therapy approach which might trigger a renewed use of neon and heavier ions to treat cancers. These ions were shown to be extremely efficient in radioresistant tumor killing. Unfortunately, the efficient region also extends into the normal tissue in front of the tumor. The strategy the authors propose is to profit from the well-established sparing effect of thin spatially fractionated beams, so that the impact on normal tissues might be minimized while a high tumor control is achieved. The main goal of this work is to provide a proof of concept of this new approach. With that aim, a dosimetric study was carried out as a first step to evaluate the interest of further explorations of this avenue.
Idioma originalInglés
Páginas (desde-hasta)5928-5936
Número de páginas9
PublicaciónMedical Physics
Volumen42
N.º10
DOI
EstadoPublicada - oct 2015

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