Resumen
Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule. © 2010 American Institute of Physics.
| Idioma original | Inglés |
|---|---|
| Número de artículo | 213701 |
| Publicación | Applied physics letters |
| Volumen | 96 |
| DOI | |
| Estado | Publicada - 24 may 2010 |