Relationship between rotational behaviour induced by apomorphine and caffeine in rats with unilateral lesion of the nigrostriatal pathway

M. Casas, S. Ferré, A. Cobos, J. M. Grau, F. Jané

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39 Citas (Scopus)

Resumen

The contralateral rotational behaviour produced by apomorphine and caffeine has been studied in 100 rats with unilateral lesion of the nigrostriatal pathway induced with 6-OHDA. Rats with a two-peak rotational pattern induced by apomorphine, showed a greater number of contralateral turns, induced by apomorphine and caffeine, than rats which did not show this rotational pattern. A correlation was observed between the number of rotations induced by apomorphine and those induced by caffeine. A relationship between the two-peak rotational pattern induced by apomorphine and the initial-peak pattern induced by caffeine was also observed. © 1989.
Idioma originalInglés
Páginas (desde-hasta)407-409
PublicaciónNeuropharmacology
Volumen28
N.º4
DOI
EstadoPublicada - 1 ene 1989

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