Keyphrases
Knock-in Mouse Model
100%
PDK1
100%
Amyloid-β Peptide
100%
Neuronal Culture
100%
Akt Activation
100%
Alzheimer's Disease Model
50%
Neuronal Survival
50%
Mutant Forms
25%
AKT Pathway
25%
Neurotoxicity
25%
Endoplasmic Reticulum
25%
Attenuation
25%
Mutant Mice
25%
Age-dependent
25%
Secretase
25%
Amyloid-β Oligomers
25%
Membrane Activity
25%
Survival Response
25%
Unfolded Protein Response
25%
PI3K Signaling Pathway
25%
Downstream Effectors
25%
TNF Receptor 1 (TNFR1)
25%
ADAM17
25%
Akt Kinase
25%
Membrane Localization
25%
Akt Stimulation
25%
Amyloid-β Pathology
25%
Aged Brain
25%
Biochemistry, Genetics and Molecular Biology
Beta-Peptide
100%
Phosphoinositide-Dependent Kinase-1
100%
Amyloid Beta
100%
Nerve Cell Culture
100%
Mouse Model
25%
Signal Transduction
25%
Secretase
25%
ADAM17
25%
Transgenic Mouse
25%
Akt Signaling
25%
Mouse Mutant
25%
Tumor Necrosis Factor
25%
Protein Unfolding
25%
Protein Kinase B
25%
Neuroscience
Phosphoinositide-Dependent Kinase-1
100%
Amyloid Beta Protein
100%
Beta Amyloid
50%
Alzheimer's Disease
50%
Cell Signaling
25%
Oligomer
25%
Endoplasmic reticulum
25%
Protein Kinase B
25%
Tumor Necrosis Factor Alpha Converting Enzyme
25%
Neurotoxicity
25%
Akt Signaling
25%
Secretase
25%
Protein Unfolding
25%