TY - JOUR
T1 - Prevalence of Candida bracarensis and Candida nivariensis in a Spanish collection of yeasts: Comparison of results from a reference centre and from a population-based surveillance study of candidemia
AU - Cuenca-Estrella, M.
AU - Gomez-Lopez, A.
AU - Isla, G.
AU - Rodriguez, D.
AU - Almirante, B.
AU - Pahissa, A.
AU - Rodriguez-Tudela, J. L.
AU - Fridkin, Scott
AU - Hajjeh, Rana
AU - Park, Benjamin
AU - Morgan, Juliette
AU - Warnock, David W.
AU - Planes, Ana Maria
AU - Almela, Manel
AU - Mensa, José
AU - Reverter, Francesc Marco
AU - Soler, C. Melcion
AU - Salvado, Margarita
AU - Saballs, P.
AU - Gener, Amadeu
AU - Fontanals, Dionisia
AU - Xercavins, Mariona
AU - Falgueras, Lluis
AU - Torroella, Maria Teresa
AU - De Ramon, Marta
AU - Alonso, Carles
AU - De Otero, Jordi
AU - Sierra, Montserrat
AU - Martinez-Montauti, Joaquin
AU - Morera, Maria Antonia
AU - Sanchez, Ferran
AU - Ayats, Josefina
AU - Gimenez, Montserrat
PY - 2011/7/1
Y1 - 2011/7/1
N2 - Two new species related to Candida glabrata, i.e., Candida nivariensis and Candida bracarensis, have been proposed. The occurrence of these species among isolates collected in a Spanish mycology reference laboratory in 2008-2009 was reviewed. In addition, strains recovered as part of an active population-based surveillance of candidemia conducted in Barcelona between 2002 and 2003 were also analyzed. Among 143 clinical isolates received in 2008-2009, three (2%) were identified as C. bracarensis and none as C. nivariensis through sequencing of their ribosomal DNA. Of the 31 strains initially identified as C. glabrata in the 2002-2003 population-based study (0.38 cases/100,000 population), none were found to belong to these related new species. Results from in vitro susceptibility studies of C. bracarensis isolates were comparable to those found with C. glabrata. Since new and cryptic species have been described, periodic surveillance including the use of molecular identification methods seems to be necessary in order to determine their frequency, geographical distribution and susceptibility profile. © 2011 ISHAM.
AB - Two new species related to Candida glabrata, i.e., Candida nivariensis and Candida bracarensis, have been proposed. The occurrence of these species among isolates collected in a Spanish mycology reference laboratory in 2008-2009 was reviewed. In addition, strains recovered as part of an active population-based surveillance of candidemia conducted in Barcelona between 2002 and 2003 were also analyzed. Among 143 clinical isolates received in 2008-2009, three (2%) were identified as C. bracarensis and none as C. nivariensis through sequencing of their ribosomal DNA. Of the 31 strains initially identified as C. glabrata in the 2002-2003 population-based study (0.38 cases/100,000 population), none were found to belong to these related new species. Results from in vitro susceptibility studies of C. bracarensis isolates were comparable to those found with C. glabrata. Since new and cryptic species have been described, periodic surveillance including the use of molecular identification methods seems to be necessary in order to determine their frequency, geographical distribution and susceptibility profile. © 2011 ISHAM.
KW - antifungal susceptibility
KW - Candida spp.
KW - emerging species
UR - https://www.scopus.com/pages/publications/79959273052
U2 - 10.3109/13693786.2010.546373
DO - 10.3109/13693786.2010.546373
M3 - Article
SN - 1369-3786
VL - 49
SP - 525
EP - 529
JO - Medical Mycology
JF - Medical Mycology
IS - 5
ER -