TY - GEN
T1 - Point-of-care microanalizer for potentiometric determination of ammonium in plasma
AU - Rebollo-Calderon, Beatriz
AU - Calvo-Lopez, Antonio
AU - Ormazabal, Aida
AU - Puyol, Mar
AU - Artuch, Rafael
AU - Alonso-Chamarro, Julian
N1 - Publisher Copyright:
© 2020 CBMS-0001
PY - 2020
Y1 - 2020
N2 - A cyclic olefin copolymer (COC)-based continuous flow potentiometric point-of-care (POC) microanalyzer is hereby presented for the bedside determination of ammonium ion in plasma of patients affected by diseases causing hyperammonemia episodes, such as urea cycle disorders (UCDs). The microanalyzer integrates microfluidics, a potentiometric detection system with an ammonium ion selective electrode (ISE) and a Ag/AgCl reference electrode, and a gas diffusion membrane to enhance selectivity avoiding matrix interferences. Real samples have been analyzed obtaining highly promising results.
AB - A cyclic olefin copolymer (COC)-based continuous flow potentiometric point-of-care (POC) microanalyzer is hereby presented for the bedside determination of ammonium ion in plasma of patients affected by diseases causing hyperammonemia episodes, such as urea cycle disorders (UCDs). The microanalyzer integrates microfluidics, a potentiometric detection system with an ammonium ion selective electrode (ISE) and a Ag/AgCl reference electrode, and a gas diffusion membrane to enhance selectivity avoiding matrix interferences. Real samples have been analyzed obtaining highly promising results.
KW - Ammonium ion
KW - Microfluidics
KW - Point-of-care
KW - Polymer technology
KW - Potentiometric detection
UR - http://www.scopus.com/inward/record.url?scp=85098261033&partnerID=8YFLogxK
M3 - Other contribution
AN - SCOPUS:85098261033
T3 - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
ER -