TY - JOUR
T1 - No-touch hepatic hilum technique to treat early portal vein thrombosis after pediatric liver transplantation
AU - Bueno, J.
AU - Perez-Lafuente, M.
AU - Venturi, C.
AU - Segarra, A.
AU - Barber, I.
AU - Molino, J. A.
AU - Romero, A.
AU - Ortega, J.
AU - Bilbao, I.
AU - Martinez-Ibañez, V.
AU - Charco, R.
PY - 2010/9/1
Y1 - 2010/9/1
N2 - A 'no-touch' hilum technique used to treat early portal vein complications post-liver transplantation in five children with body weight <10 kg is described. Four patients developed thrombosis and one portal flow absence secondary to collateral steal flow. A vascular sheath was placed through the previous laparotomy in the ileocolic vein (n = 2), inferior mesenteric vein (n = 1) or graft umbilical vein (n = 1). Portal clots were mechanically fragmented with balloon angioplasty. In addition, coil embolization of competitive collaterals (n = 3) and stent placement (n = 1) were performed. The catheter was left in place and exteriorized through the wound (n = 2) or a different transabdominal wall puncture (n = 3). A continuous transcatheter perfusion of heparin was subsequently administered. One patient developed recurrent thrombosis 24 h later which was resolved with the same technique. Catheters were removed surgically after a mean of 10.6 days. All patients presented portal vein patency at the end of follow-up. Three patients are alive after 5 months, 1.5 and 3.5 years, respectively; one patient required retransplantation 18 days postprocedure and the remaining patient died of adenovirus infection 2 months postprocedure. In conclusion, treatment of early portal vein complications following pediatric liver transplantation with this novel technique is feasible and effective. © 2010 The American Society of Transplantation and the American Society of Transplant Surgeons.
AB - A 'no-touch' hilum technique used to treat early portal vein complications post-liver transplantation in five children with body weight <10 kg is described. Four patients developed thrombosis and one portal flow absence secondary to collateral steal flow. A vascular sheath was placed through the previous laparotomy in the ileocolic vein (n = 2), inferior mesenteric vein (n = 1) or graft umbilical vein (n = 1). Portal clots were mechanically fragmented with balloon angioplasty. In addition, coil embolization of competitive collaterals (n = 3) and stent placement (n = 1) were performed. The catheter was left in place and exteriorized through the wound (n = 2) or a different transabdominal wall puncture (n = 3). A continuous transcatheter perfusion of heparin was subsequently administered. One patient developed recurrent thrombosis 24 h later which was resolved with the same technique. Catheters were removed surgically after a mean of 10.6 days. All patients presented portal vein patency at the end of follow-up. Three patients are alive after 5 months, 1.5 and 3.5 years, respectively; one patient required retransplantation 18 days postprocedure and the remaining patient died of adenovirus infection 2 months postprocedure. In conclusion, treatment of early portal vein complications following pediatric liver transplantation with this novel technique is feasible and effective. © 2010 The American Society of Transplantation and the American Society of Transplant Surgeons.
KW - Angioplasty
KW - biliary atresia
KW - children
KW - liver transplantation
KW - portal vein thrombosis
UR - https://www.scopus.com/pages/publications/77956156987
U2 - 10.1111/j.1600-6143.2010.03236.x
DO - 10.1111/j.1600-6143.2010.03236.x
M3 - Article
SN - 1600-6135
VL - 10
SP - 2148
EP - 2153
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 9
ER -