New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia

Sergi Montero; M. Rosa Caballín; M. Dolors Coll; Carles Besses; Soledad Woessner; Josep Egozcue; Francesc Solé

doi:10.1016/0165-4608(92)90004-R

New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia

Sergi Montero, M. Rosa Caballín, M. Dolors Coll, Carles Besses, Soledad Woessner, Josep Egozcue, Francesc Solé

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

Resumen

Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. © 1992.

Idioma original	Inglés
Páginas (desde-hasta)	131-134
Publicación	Cancer Genetics and Cytogenetics
Volumen	60
N.º	2
DOI	https://doi.org/10.1016/0165-4608(92)90004-R
Estado	Publicada - 1 ene 1992

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title = "New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia",

abstract = "Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. {\textcopyright} 1992.",

author = "Sergi Montero and Caball{\'i}n, {M. Rosa} and Coll, {M. Dolors} and Carles Besses and Soledad Woessner and Josep Egozcue and Francesc Sol{\'e}",

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doi = "10.1016/0165-4608(92)90004-R",

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T1 - New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia

AU - Montero, Sergi

AU - Caballín, M. Rosa

AU - Coll, M. Dolors

AU - Besses, Carles

AU - Woessner, Soledad

AU - Egozcue, Josep

AU - Solé, Francesc

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. © 1992.

AB - Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. © 1992.

U2 - 10.1016/0165-4608(92)90004-R

DO - 10.1016/0165-4608(92)90004-R

M3 - Article

SN - 0165-4608

VL - 60

SP - 131

EP - 134

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 2

ER -

New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia

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