Neuropsychiatric symptoms associated with efavirenz: Prevalence, correlates and management. A neurobehavioral review

José A. Muñoz-Moreno; Carmina R. Fumaz; Maria J. Ferrer; Marian González-Garcia; José Moltó; Eugènia Negredo; Bonaventura Clotet

Neuropsychiatric symptoms associated with efavirenz: Prevalence, correlates and management. A neurobehavioral review

José A. Muñoz-Moreno, Carmina R. Fumaz, Maria J. Ferrer, Marian González-Garcia, José Moltó, Eugènia Negredo, Bonaventura Clotet

Departamento de Medicina

Producción científica: Contribución a una revista › Artículo de revisión › Investigación › revisión exhaustiva

72 Citas (Scopus)

Resumen

The non-nucleoside analog reverse transcriptase inhibitor efavirenz is one of the most common components of HAART. Neuropsychiatric symptoms are frequently reported in patients taking efavirenzbased regimens. These symptoms are usually transient, although they can sometimes persist for up to two years after initiation of treatment. This review describes in detail the most common neuropsychiatric symptoms related to efavirenz, outlines relevant and recent findings on this agent, and suggests possible interventions based on neurobehavioral results. Different recommendations on the assessment of efavirenz-related adverse events are also provided.

Idioma original	Inglés
Páginas (desde-hasta)	103-109
Publicación	AIDS Reviews
Volumen	11
N.º	2
Estado	Publicada - 15 sept 2009

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title = "Neuropsychiatric symptoms associated with efavirenz: Prevalence, correlates and management. A neurobehavioral review",

abstract = "The non-nucleoside analog reverse transcriptase inhibitor efavirenz is one of the most common components of HAART. Neuropsychiatric symptoms are frequently reported in patients taking efavirenzbased regimens. These symptoms are usually transient, although they can sometimes persist for up to two years after initiation of treatment. This review describes in detail the most common neuropsychiatric symptoms related to efavirenz, outlines relevant and recent findings on this agent, and suggests possible interventions based on neurobehavioral results. Different recommendations on the assessment of efavirenz-related adverse events are also provided.",

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AU - Muñoz-Moreno, José A.

AU - Fumaz, Carmina R.

AU - Ferrer, Maria J.

AU - González-Garcia, Marian

AU - Moltó, José

AU - Negredo, Eugènia

AU - Clotet, Bonaventura

PY - 2009/9/15

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N2 - The non-nucleoside analog reverse transcriptase inhibitor efavirenz is one of the most common components of HAART. Neuropsychiatric symptoms are frequently reported in patients taking efavirenzbased regimens. These symptoms are usually transient, although they can sometimes persist for up to two years after initiation of treatment. This review describes in detail the most common neuropsychiatric symptoms related to efavirenz, outlines relevant and recent findings on this agent, and suggests possible interventions based on neurobehavioral results. Different recommendations on the assessment of efavirenz-related adverse events are also provided.

AB - The non-nucleoside analog reverse transcriptase inhibitor efavirenz is one of the most common components of HAART. Neuropsychiatric symptoms are frequently reported in patients taking efavirenzbased regimens. These symptoms are usually transient, although they can sometimes persist for up to two years after initiation of treatment. This review describes in detail the most common neuropsychiatric symptoms related to efavirenz, outlines relevant and recent findings on this agent, and suggests possible interventions based on neurobehavioral results. Different recommendations on the assessment of efavirenz-related adverse events are also provided.

KW - Antiretroviral therapy

KW - Efavirenz

KW - HIV infection

M3 - Review article

SN - 1139-6121

VL - 11

SP - 103

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JO - AIDS Reviews

JF - AIDS Reviews

IS - 2

ER -

Neuropsychiatric symptoms associated with efavirenz: Prevalence, correlates and management. A neurobehavioral review

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