TY - JOUR
T1 - Nanodiagnostics to face SARS-CoV-2 and future pandemics :
T2 - from an idea to the market and beyond
AU - Rosati, Giulio
AU - Idili, Andrea
AU - Parolo, Claudio
AU - Fuentes-Chust, Celia
AU - Calucho, Enric
AU - Hu, Liming
AU - De Carvalho Castro Silva, Cecilia
AU - Rivas, Lourdes
AU - Nguyen, Emily P.
AU - Bergua Canudo, José Francisco
AU - Álvarez Diduk, Ruslan
AU - Muñoz, José
AU - Junot, Christophe
AU - Penon, Oriol
AU - Monferrer, Dominique
AU - Delamarche, Emmanuel
AU - Merkoçi, Arben
PY - 2021
Y1 - 2021
N2 - The COVID-19 pandemic made clear how our society requires quickly available tools to address emerging healthcare issues. Diagnostic assays and devices are used every day to screen for COVID-19 positive patients, with the aim to decide the appropriate treatment and containment measures. In this context, we would have expected to see the use of the most recent diagnostic technologies worldwide, including the advanced ones such as nano-biosensors capable to provide faster, more sensitive, cheaper, and high-throughput results than the standard polymerase chain reaction and lateral flow assays. Here we discuss why that has not been the case and why all the exciting diagnostic strategies published on a daily basis in peer-reviewed journals are not yet successful in reaching the market and being implemented in the clinical practice.
AB - The COVID-19 pandemic made clear how our society requires quickly available tools to address emerging healthcare issues. Diagnostic assays and devices are used every day to screen for COVID-19 positive patients, with the aim to decide the appropriate treatment and containment measures. In this context, we would have expected to see the use of the most recent diagnostic technologies worldwide, including the advanced ones such as nano-biosensors capable to provide faster, more sensitive, cheaper, and high-throughput results than the standard polymerase chain reaction and lateral flow assays. Here we discuss why that has not been the case and why all the exciting diagnostic strategies published on a daily basis in peer-reviewed journals are not yet successful in reaching the market and being implemented in the clinical practice.
KW - COVID-19
KW - SARS-CoV-2
KW - Nanodiagnostics
KW - Biosensors
KW - Bottlenecks
KW - Outbreaks
KW - Testing methods
KW - Phases of test development
UR - https://www.scopus.com/pages/publications/85118930117
U2 - 10.1021/acsnano.1c06839
DO - 10.1021/acsnano.1c06839
M3 - Article
C2 - 34705433
SN - 1936-0851
VL - 15
SP - 17137
EP - 17149
JO - ACS Nano
JF - ACS Nano
IS - 11
ER -