TY - JOUR
T1 - Malignant pheochromocytoma in a pig
AU - Martínez, Jorge
AU - Galindo-Cardiel, Iván
AU - Díez-Padrisa, Meritxell
AU - López-Sabater, Emilio I.
AU - Segalés, Joaquim
PY - 2012/1/1
Y1 - 2012/1/1
N2 - Endocrine tumors are rarely observed in pigs, and pheochromocytomas have been only punctually described. The current report describes a white and firm, 15-cm in diameter, neoplastic mass located in the adrenal gland with metastasis to regional lymph nodes in a 2.5-year-old sow. The masses had marked desmoplasia that supported a population of polygonal-to-spindle-shaped neoplastic cells arranged into cords and packets within a delicate fibrovascular stroma. Immunohistochemical staining of the tumor was positive for chromogranin and negative for neurofilament protein in adrenal and lymph node masses, which was characteristic of a malignant pheochromocytoma. © 2012 American Association of Veterinary Laboratory Diagnosticians.
AB - Endocrine tumors are rarely observed in pigs, and pheochromocytomas have been only punctually described. The current report describes a white and firm, 15-cm in diameter, neoplastic mass located in the adrenal gland with metastasis to regional lymph nodes in a 2.5-year-old sow. The masses had marked desmoplasia that supported a population of polygonal-to-spindle-shaped neoplastic cells arranged into cords and packets within a delicate fibrovascular stroma. Immunohistochemical staining of the tumor was positive for chromogranin and negative for neurofilament protein in adrenal and lymph node masses, which was characteristic of a malignant pheochromocytoma. © 2012 American Association of Veterinary Laboratory Diagnosticians.
KW - Adrenal gland
KW - metastasis
KW - paraganglioma
KW - pheochromocytoma
KW - swine
U2 - 10.1177/1040638711425949
DO - 10.1177/1040638711425949
M3 - Article
SN - 1040-6387
VL - 24
SP - 207
EP - 210
JO - Journal of Veterinary Diagnostic Investigation
JF - Journal of Veterinary Diagnostic Investigation
IS - 1
ER -