Resumen
© 2018 Elsevier Inc. This study aimed to assess antioxidant and immune gene transcription alterations in the gills of Sparus aurata exposed during 96 h to 4, 80, and 1600 μg/L of gold nanoparticles (AuNPs) coated with citrate or polyvinyl pyrrolidone (PVP). After 96 h of exposure, gr and cat mRNA levels decreased for all tested concentrations of AuNPs, for both coatings. Instead, gst3 mRNA increased after exposure to 1600 μg/L AuNPs (both coatings) and prdx6 increased after exposure to 1600 μg/L AuNPs-citrate. Concerning immune genes, il1β mRNA levels increased after exposure to 80 μg/L AuNPs-citrate and 1600 μg/L AuNPs-PVP and cox2 mRNA showed increased levels in fish exposed to 1600 μg/L AuNPs-citrate. Results indicate that AuNPs with distinct coatings induced different gene expression profiles in gills, though most of the studied genes remained unaltered for the tested conditions.
Idioma original | Inglés |
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Páginas (desde-hasta) | 430-434 |
Publicación | Genomics |
Volumen | 110 |
DOI | |
Estado | Publicada - 1 nov 2018 |