Fragile sites, chromosome evolution, and human neoplasia

Rosa Miró; Inmaculada Concepción Clemente; Carmen Fuster; José Egozcue

doi:10.1007/BF00284105

Fragile sites, chromosome evolution, and human neoplasia

Rosa Miró, Inmaculada Concepción Clemente, Carmen Fuster, José Egozcue

Instituto de Biotecnología y de Biomedicina "Vicent Villar Palasi" (IBB)

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

65 Citas (Scopus)

Resumen

In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

Idioma original	Inglés
Páginas (desde-hasta)	345-349
Publicación	Human Genetics
Volumen	75
N.º	4
DOI	https://doi.org/10.1007/BF00284105
Estado	Publicada - 1 abr 1987

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title = "Fragile sites, chromosome evolution, and human neoplasia",

abstract = "In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. {\textcopyright} 1987 Springer-Verlag.",

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AU - Miró, Rosa

AU - Clemente, Inmaculada Concepción

AU - Fuster, Carmen

AU - Egozcue, José

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Y1 - 1987/4/1

N2 - In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

AB - In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates. © 1987 Springer-Verlag.

UR - https://www.scopus.com/pages/publications/0023090923

U2 - 10.1007/BF00284105

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JO - Human Genetics

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Fragile sites, chromosome evolution, and human neoplasia

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