Enhancing biological tissue structures visualization through polarimetric parameters

Mónica Canabal-Carbia*, Carla Rodriguez, Irene Estévez, Albert Van Eeckout, Emilio González-Arnay, Enrique García-Caurel, Teresa Garnatje, Juan Campos, Angel Lizana

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículoInvestigaciónrevisión exhaustiva

3 Citas (Scopus)

Resumen

Polarimetrical imaging is a noninvasive optical technique of great interest in biophotonics since it has the capability of obtaining relevant information of biological samples, being useful, for instance, for the early detection of diseases or the classification of biological structures, both on animal and vegetal tissues. Different structures produce different outcomes when interacting with light due to their polarimetric properties such as depolarization, dichroism or retardance. An exhaustive polarimetric analysis of these characteristics can unveil the relation between the tissue inherent characteristics and its polarimetric response, enabling us to find the most appropriate polarimetric parameters to describe or study a sample. These polarimetric characteristics can be obtained through the experimental measurement of the Mueller matrix (M) of a sample, from which a range of different polarimetric observables, giving physical interpretation, can be deduced. By taking advantage of these parameters, we propose a study of the suitability of different groups of metrics for the contrast enhancement in biological tissues imaging, taking special attention on some depolarization metrics and some physical parameters such as the wavelength or the angle of incidence of the illumination light. The results obtained suggest the convenience of certain parameters which may be of interest in multiple biomedical scenarios such as pathology early detection or enhanced visualization of different structures for clinical applications.

Idioma originalInglés
Número de páginas1238205
PublicaciónProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volumen12382
DOI
EstadoPublicada - 2023

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