TY - JOUR
T1 - Effect of cycloheximide on different stages of Drosophila melanogaster
AU - Marcos, R.
AU - Lloberas, J.
AU - Creus, A.
AU - Xamena, N.
AU - Cabré, O.
PY - 1982/1/1
Y1 - 1982/1/1
N2 - Cycloheximide, an antibiotic inhibiting protein synthesis, exerted a toxic effect on different developmental stages egg, larva and adult of Drosophila melanogaster. At the egg stage the early embryos were most sensitive. With larvae, a strong decrease in viability was found, with no sex difference. In adults, there was a dose-effect relationship, mortality increasing with concentration. At 10 and 15 mM, males were more sensitive than females. There were consistent differences between the control and cycloheximide-fed females in respect of the average number of eggs deposited and offspring produced. © 1982.
AB - Cycloheximide, an antibiotic inhibiting protein synthesis, exerted a toxic effect on different developmental stages egg, larva and adult of Drosophila melanogaster. At the egg stage the early embryos were most sensitive. With larvae, a strong decrease in viability was found, with no sex difference. In adults, there was a dose-effect relationship, mortality increasing with concentration. At 10 and 15 mM, males were more sensitive than females. There were consistent differences between the control and cycloheximide-fed females in respect of the average number of eggs deposited and offspring produced. © 1982.
UR - https://www.scopus.com/pages/publications/0020460227
U2 - 10.1016/0378-4274(82)90145-X
DO - 10.1016/0378-4274(82)90145-X
M3 - Article
SN - 0378-4274
VL - 13
SP - 105
EP - 112
JO - Toxicology Letters
JF - Toxicology Letters
ER -