Determination of ascorbic acid in pharmaceutical preparations by near infrared reflectance spectroscopy

M. Blanco, J. Coello, H. Iturriaga, S. Maspoch, C. de la Pezuela

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33 Citas (Scopus)

Resumen

We developed a method for determination of ascorbic acid in pharmaceutical preparations containing various excipients by using near infrared diffuse reflectance spectroscopy and two different calibration methods, viz. stepwise multiple linear regression (SMLR) and partial least-squares (PLS) regression, which provided comparable results and resulted in prediction errors of 1-2%. However, the PLS method provided somewhat better results with the more complex samples. © 1993.
Idioma originalInglés
Páginas (desde-hasta)1671-1676
PublicaciónTalanta
Volumen40
N.º11
DOI
EstadoPublicada - 1 ene 1993

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