TY - JOUR
T1 - Current developments in homonuclear and heteronuclear J-resolved NMR experiments
AU - Parella, Teodor
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Copyright © 2018 John Wiley & Sons, Ltd. Two-dimensional J-resolved (Jres) NMR experiments offer a simple, user-friendly spectral representation where the information of coupling constants and chemical shifts are separated into two orthogonal frequency axis. Since its initial proposal 40 years ago, Jres has been the focus of considerable interest both in improving the basic pulse sequence and in its successful application to a wide range of studies. Here, the latest developments in the design of novel Jres pulse schemes are reviewed, mainly focusing on obtaining pure absorption lineshapes, minimizing strong coupling artifacts, and also optimizing sensitivity and experimental measurements. A discussion of several Jres versions for the accurate measurement of a different number of homonuclear (JHH) and heteronuclear (JCH) coupling constants is presented, accompanied by some illustrative examples.
AB - Copyright © 2018 John Wiley & Sons, Ltd. Two-dimensional J-resolved (Jres) NMR experiments offer a simple, user-friendly spectral representation where the information of coupling constants and chemical shifts are separated into two orthogonal frequency axis. Since its initial proposal 40 years ago, Jres has been the focus of considerable interest both in improving the basic pulse sequence and in its successful application to a wide range of studies. Here, the latest developments in the design of novel Jres pulse schemes are reviewed, mainly focusing on obtaining pure absorption lineshapes, minimizing strong coupling artifacts, and also optimizing sensitivity and experimental measurements. A discussion of several Jres versions for the accurate measurement of a different number of homonuclear (JHH) and heteronuclear (JCH) coupling constants is presented, accompanied by some illustrative examples.
KW - GSERF
KW - J-resolved
KW - J-resolved HSQC
KW - proton–carbon coupling constants
KW - proton–proton coupling constants
KW - residual dipolar couplings
U2 - 10.1002/mrc.4706
DO - 10.1002/mrc.4706
M3 - Review article
C2 - 29314247
SN - 0749-1581
VL - 56
SP - 230
EP - 250
JO - Magnetic Resonance in Chemistry
JF - Magnetic Resonance in Chemistry
IS - 4
ER -