Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

Ming Liu; Axel Guinart Guillem; Albert Granados Toda; Carolina Gimbert Suriñach; Ester Fernandez; Roser Pleixats i Rovira; Adelina Vallribera Massó

doi:10.1021/acsami.4c00383

Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

Ming Liu, Axel Guinart Guillem, Albert Granados Toda, Carolina Gimbert Suriñach, Ester Fernandez, Roser Pleixats i Rovira, Adelina Vallribera Massó

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

27 Citas (Scopus)

Resumen

Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

Idioma original	Inglés
Páginas (desde-hasta)	14595-14604
Número de páginas	10
Publicación	ACS applied materials & interfaces
Volumen	16
N.º	12
DOI	https://doi.org/10.1021/acsami.4c00383
Estado	Publicada - 12 mar 2024

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10.1021/acsami.4c00383

https://ddd.uab.cat/record/291542

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METODOS EMERGENTES PARA LA INTRODUCCION DE GRUPOS (PER)FLUORADOS. FOTOCATALISIS
Vallribera Masso, A. (Investigador/a principal), Pleixats Rovira, R. (Investigador/a), Granados Toda, A. (Investigador/a), Liu, M. Z. (Colaborador/a), Tan, X. (Colaborador/a) & Ji , Y. (Colaborador/a)
Fondo Europeo de Desarrollo Regional (FEDER)
1/09/22 → 31/08/25
Proyecto: Proyectos y Ayudas de Investigación
QUIMICA ORGANOFLUORADA: METODOS EMERGENTES DE FLUORACION Y TEJIDOS DE ALGODON PARA USOS MEDICOS
Vallribera Masso, A. (Investigador/a principal), Pleixats Rovira, R. (Co-Investigador/a Principal), Fernandez Freixes, G. (Colaborador/a), Granados Toda, A. (Colaborador/a), Li , H. (Colaborador/a), Liu, M. (Colaborador/a), Gimbert Suriñach, C. (Colaborador/a) & Gallego Gamo, A. (Colaborador/a)
Ministerio de Economía y Competitividad (MINECO), Fondo Europeo de Desarrollo Regional (FEDER)
1/01/19 → 30/09/22
Proyecto: Proyectos y Ayudas de Investigación

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@article{d669dbef0e9e4e54855e653f8297c9f6,

title = "Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing",

abstract = "Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.",

keywords = "amide groups, anti-inflammatory, antimicrobial, cotton wound dressing, enzymatic cleavage, ibuprofen, norfloxacin, silica nanoparticles",

author = "Ming Liu and \{Guinart Guillem\}, Axel and \{Granados Toda\}, Albert and \{Gimbert Suri{\~n}ach\}, Carolina and Ester Fernandez and \{Pleixats i Rovira\}, Roser and \{Vallribera Mass{\'o}\}, Adelina",

note = "Publisher Copyright: {\textcopyright} 2024 The Authors. Published by American Chemical Society",

year = "2024",

month = mar,

day = "12",

doi = "10.1021/acsami.4c00383",

language = "English",

volume = "16",

pages = "14595--14604",

journal = "ACS applied materials \& interfaces",

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Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing. / Liu, Ming; Guinart Guillem, Axel; Granados Toda, Albert et al.
En: ACS applied materials & interfaces, Vol. 16, N.º 12, 12.03.2024, p. 14595-14604.

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

TY - JOUR

T1 - Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

AU - Liu, Ming

AU - Guinart Guillem, Axel

AU - Granados Toda, Albert

AU - Gimbert Suriñach, Carolina

AU - Fernandez, Ester

AU - Pleixats i Rovira, Roser

AU - Vallribera Massó, Adelina

PY - 2024/3/12

Y1 - 2024/3/12

N2 - Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

AB - Herein, we report the preparation of bifunctional silica nanoparticles by covalent attachment of both an anti-inflammatory drug (ibuprofen) and an antibiotic (levofloxacin or norfloxacin) through amide groups. We also describe the coating of cotton fabrics with silica nanoparticles containing both ibuprofen and norfloxacin moieties linked by amide groups by using a one-step coating procedure under ultrasonic conditions. The functionalized nanoparticles and cotton fabrics have been characterized using spectroscopic and microscopic techniques. The functionalized nanoparticles and textiles have been treated with model proteases for the in situ release of the drugs by the amide bond enzymatic cleavage. Topical dermal applications in medical bandages are expected, which favor wound healing.

KW - amide groups

KW - anti-inflammatory

KW - antimicrobial

KW - cotton wound dressing

KW - enzymatic cleavage

KW - ibuprofen

KW - norfloxacin

KW - silica nanoparticles

UR - https://www.scopus.com/pages/publications/85187569992

UR - https://www.mendeley.com/catalogue/0e8c2a92-0f3d-3fec-a1a3-b65d7bc5b023/

U2 - 10.1021/acsami.4c00383

DO - 10.1021/acsami.4c00383

M3 - Article

C2 - 38469717

SN - 1944-8252

VL - 16

SP - 14595

EP - 14604

JO - ACS applied materials & interfaces

JF - ACS applied materials & interfaces

IS - 12

ER -

Coated Cotton Fabrics with Antibacterial and Anti-Inflammatory Silica Nanoparticles for Improving Wound Healing

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METODOS EMERGENTES PARA LA INTRODUCCION DE GRUPOS (PER)FLUORADOS. FOTOCATALISIS

QUIMICA ORGANOFLUORADA: METODOS EMERGENTES DE FLUORACION Y TEJIDOS DE ALGODON PARA USOS MEDICOS

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