Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin :: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

Amy K. Saenger; Allan S. Jaffe; Richard Body; Paul O. Collinson; Peter A. Kavsak; Carolyn S. P. Lam; Guillaume Lefèvre; Tobjørn Omland; Jorge Ordoñez Llanos; Kari Pulkki; Fred S. Apple

doi:10.1515/cclm-2018-0905

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

Amy K. Saenger, Allan S. Jaffe, Richard Body, Paul O. Collinson, Peter A. Kavsak, Carolyn S. P. Lam, Guillaume Lefèvre, Tobjørn Omland, Jorge Ordoñez Llanos, Kari Pulkki, Fred S. Apple

Departamento de Bioquímica y Biología Molecular

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

33 Citas (Scopus)

Resumen

Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.

Idioma original	Inglés
Páginas (desde-hasta)	633-640
Número de páginas	8
Publicación	Clinical Chemistry and Laboratory Medicine
Volumen	57
N.º	5
DOI	https://doi.org/10.1515/cclm-2018-0905
Estado	Publicada - 2019

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Saenger, A. K., Jaffe, A. S., Body, R., Collinson, P. O., Kavsak, P. A., Lam, C. S. P., Lefèvre, G., Omland, T., Ordoñez Llanos, J., Pulkki, K., & Apple, F. S. (2019). Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB). Clinical Chemistry and Laboratory Medicine, 57(5), 633-640. https://doi.org/10.1515/cclm-2018-0905

@article{fd5b31b7df334661b3670e906b563918,

title = "Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin :: educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)",

abstract = "Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.",

keywords = "Biotin, Hemolysis, Interferences, Natriuretic, Peptide, Troponin",

author = "Saenger, {Amy K.} and Jaffe, {Allan S.} and Richard Body and Collinson, {Paul O.} and Kavsak, {Peter A.} and Lam, {Carolyn S. P.} and Guillaume Lef{\`e}vre and Tobj{\o}rn Omland and {Ordo{\~n}ez Llanos}, Jorge and Kari Pulkki and Apple, {Fred S.}",

year = "2019",

doi = "10.1515/cclm-2018-0905",

language = "English",

volume = "57",

pages = "633--640",

number = "5",

}

Saenger, AK, Jaffe, AS, Body, R, Collinson, PO, Kavsak, PA, Lam, CSP, Lefèvre, G, Omland, T, Ordoñez Llanos, J, Pulkki, K & Apple, FS 2019, 'Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)', Clinical Chemistry and Laboratory Medicine, vol. 57, n.º 5, pp. 633-640. https://doi.org/10.1515/cclm-2018-0905

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB). / Saenger, Amy K.; Jaffe, Allan S.; Body, Richard et al.
En: Clinical Chemistry and Laboratory Medicine, Vol. 57, N.º 5, 2019, p. 633-640.

Producción científica: Contribución a una revista › Artículo › Investigación › revisión exhaustiva

TY - JOUR

T1 - Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin :

T2 - educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

AU - Saenger, Amy K.

AU - Jaffe, Allan S.

AU - Body, Richard

AU - Collinson, Paul O.

AU - Kavsak, Peter A.

AU - Lam, Carolyn S. P.

AU - Lefèvre, Guillaume

AU - Omland, Tobjørn

AU - Ordoñez Llanos, Jorge

AU - Pulkki, Kari

AU - Apple, Fred S.

PY - 2019

Y1 - 2019

N2 - Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.

AB - Two interferences recently brought to the forefront as patient safety issues include hemolysis (hemoglobin) and biotin (vitamin B7). The International Federation for Clinical Chemistry Committee on Cardiac Biomarkers (IFCC-CB) obtained input from a majority of cTn and NP assay manufacturers to collate information related to high-sensitivity (hs)-cTnI, hs-cTnT, contemporary, and POC cTn assays, and NP assays interferences due to hemolysis and biotin. The information contained in these tables was designed as educational tools to aid laboratory professionals and clinicians in troubleshooting cardiac biomarker analytical results that are discordant with the clinical situation.

KW - Biotin

KW - Hemolysis

KW - Interferences

KW - Natriuretic

KW - Peptide

KW - Troponin

U2 - 10.1515/cclm-2018-0905

DO - 10.1515/cclm-2018-0905

M3 - Article

C2 - 30291783

SN - 1434-6621

VL - 57

SP - 633

EP - 640

JO - Clinical Chemistry and Laboratory Medicine

JF - Clinical Chemistry and Laboratory Medicine

IS - 5

ER -

Cardiac troponin and natriuretic peptide analytical interferences from hemolysis and biotin : educational aids from the IFCC Committee on Cardiac Biomarkers (IFCC C-CB)

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