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Biodose Tools updates for criticality accidents and interlaboratory comparisons

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Resumen

Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3.7.1, mainly focuses on new features related to large-scale emergency responses, like criticality accidents dose estimation and laboratory networks.
Material and Methods: Biodose Tools has been developed using the R programming language. The current version (3.7.1) uses the same external dependencies as version 3.6.1 (released November 2022) while integrating three new external packages to support the new functionalities.
Results: Version 3.7.1 introduces different new modules: (a) a characteristic limits module that calculates decision thresholds and detection limits following ISO19238:2023 standards, and offers statistical tests to compare rates between suspected exposure cases and control data; (b) an enhanced dose estimation module which supports multiple dose assessments for dicentric and translocation assays for various exposure scenarios: acute, protracted, and highly protracted, as well as whole and partial-body exposures; (c) a criticality accidents module for multiple dose estimations using dicentrics in mixed gamma-neutron exposure scenarios (e.g. nuclear detonations); and (d) an Interlaboratory comparison module that automates the evaluation and comparison of dose estimates across laboratories.
Conclusions: Biodose Tools (https://www.reneb.net/software/) continues to evolve in response to the dynamic needs of the biological dosimetry community, contributing to the preparedness and consistency in emergency response and routine applications.
Idioma originalInglés
Páginas (desde-hasta)333-345
Número de páginas13
PublicaciónInternational Journal of Radiation Biology
Volumen102
N.º4
DOI
EstadoPublicada - 22 ene 2026

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