Zn- and Cd-metallothionein recombinant species from the most diverse phyla may contain sulfide (S2-) ligands

Mercè Capdevila; Ayelén Pagani; Laura Tío; Laura Villarreal; Sílvia Atrian; Jordi Domènech Casal

doi:10.1002/anie.200501183

Zn- and Cd-metallothionein recombinant species from the most diverse phyla may contain sulfide (S^2-) ligands

Mercè Capdevila, Ayelén Pagani, Laura Tío, Laura Villarreal, Sílvia Atrian, Jordi Domènech Casal

Research output: Contribution to journal › Article › Research › peer-review

68 Citations (Scopus)

Abstract

A sulfide surprise: The analysis of ZnII-, CdII-, and CuI-MT recombinant preparations of metallothioneins (MTs) from many organisms provides clear evidence that sulfide ions are present in nearly all their physiologically stable ZnII-MT and CdII-MT complexes (see picture), but in none of the CuI-MT species. The features of the MT complexes are in good correla(Chemical Equation Presented) tion with those reported for plant and yeast ZnII- or CdII-γ- glutamyl peptides. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

Original language	English
Pages (from-to)	4618-4622
Journal	Angewandte Chemie - International Edition
Volume	44
Issue number	29
DOIs	https://doi.org/10.1002/anie.200501183
Publication status	Published - 18 Jul 2005

Keywords

Bioinorganic chemistry
Cadmium
Metallothioneins
S ligands
Zinc

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10.1002/anie.200501183

Cite this

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title = "Zn- and Cd-metallothionein recombinant species from the most diverse phyla may contain sulfide (S2-) ligands",

abstract = "A sulfide surprise: The analysis of ZnII-, CdII-, and CuI-MT recombinant preparations of metallothioneins (MTs) from many organisms provides clear evidence that sulfide ions are present in nearly all their physiologically stable ZnII-MT and CdII-MT complexes (see picture), but in none of the CuI-MT species. The features of the MT complexes are in good correla(Chemical Equation Presented) tion with those reported for plant and yeast ZnII- or CdII-γ- glutamyl peptides. {\textcopyright} 2005 Wiley-VCH Verlag GmbH & Co. KGaA.",

keywords = "Bioinorganic chemistry, Cadmium, Metallothioneins, S ligands, Zinc",

author = "Merc{\`e} Capdevila and Ayel{\'e}n Pagani and Laura T{\'i}o and Laura Villarreal and S{\'i}lvia Atrian and {Dom{\`e}nech Casal}, Jordi",

year = "2005",

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doi = "10.1002/anie.200501183",

language = "English",

volume = "44",

pages = "4618--4622",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

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Zn- and Cd-metallothionein recombinant species from the most diverse phyla may contain sulfide (S^2-) ligands. / Capdevila, Mercè; Pagani, Ayelén; Tío, Laura; Villarreal, Laura; Atrian, Sílvia; Domènech Casal, Jordi.

In: Angewandte Chemie - International Edition, Vol. 44, No. 29, 18.07.2005, p. 4618-4622.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Zn- and Cd-metallothionein recombinant species from the most diverse phyla may contain sulfide (S2-) ligands

AU - Capdevila, Mercè

AU - Pagani, Ayelén

AU - Tío, Laura

AU - Villarreal, Laura

AU - Atrian, Sílvia

AU - Domènech Casal, Jordi

PY - 2005/7/18

Y1 - 2005/7/18

N2 - A sulfide surprise: The analysis of ZnII-, CdII-, and CuI-MT recombinant preparations of metallothioneins (MTs) from many organisms provides clear evidence that sulfide ions are present in nearly all their physiologically stable ZnII-MT and CdII-MT complexes (see picture), but in none of the CuI-MT species. The features of the MT complexes are in good correla(Chemical Equation Presented) tion with those reported for plant and yeast ZnII- or CdII-γ- glutamyl peptides. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

AB - A sulfide surprise: The analysis of ZnII-, CdII-, and CuI-MT recombinant preparations of metallothioneins (MTs) from many organisms provides clear evidence that sulfide ions are present in nearly all their physiologically stable ZnII-MT and CdII-MT complexes (see picture), but in none of the CuI-MT species. The features of the MT complexes are in good correla(Chemical Equation Presented) tion with those reported for plant and yeast ZnII- or CdII-γ- glutamyl peptides. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

KW - Bioinorganic chemistry

KW - Cadmium

KW - Metallothioneins

KW - S ligands

KW - Zinc

U2 - 10.1002/anie.200501183

DO - 10.1002/anie.200501183

M3 - Article

VL - 44

SP - 4618

EP - 4622

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 29