When does human brain development end? Evidence of corpus callosum growth up to adulthood

Jesús Pujol, Pere Vendrell, Carme Junqué, Josep L. Martí‐Vilalta, Antoni Capdevila

Research output: Contribution to journalArticleResearchpeer-review

292 Citations (Scopus)

Abstract

To locate structural changes in the brain accounting for the increasing effectiveness in cognition and skills that occurs at the final stage of behavioral development, we attempted to determine the age at which the corpus callosum completes its active growth period. We assessed the growth rate of the corpus callosum by measuring its area twice on midsagittal magnetic resonance imaging scans separated by a 2‐year interval, in a series of 90 subjects with a wide range of ages. We observed an increase in the size of the corpus callosum as long as human mentation expands, up to the middle 20s. Clinical and experimental data about the corpus callosum, together with the present findings, suggest that the corpus callosum is part of the highest order‐latest maturing neural network of the brain. Copyright © 1993 American Neurological Association
Original languageEnglish
Pages (from-to)71-75
JournalAnnals of Neurology
Volume34
Issue number1
DOIs
Publication statusPublished - 1 Jan 1993

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