© 2012 Sociedad Española de Senologña y Patología Mamaria Objective To review the series of our centre in order to determine how many patients would have had residual disease in the axilla if we had applied the criteria of the Z0011 study. Material and methods Retrospective study of sentinel lymph nodes performed in T1 and T2 breast infiltrating carcinomas in our Breast Pathology Unit between June 2008 and December 2010. We reviewed all the sentinel nodes (SN) and axillary lymph node dissections (ALND) performed when 2 or less SN were positive. Results Of 194 sentinel nodes reviewed, 33 were positive in two nodes or less (12.3%). ALND was positive in 13 cases of 33 (39.3%). Positive ALND occurred more frequently in patients ≤ 50 years old than in > 50 years old patients (53.84% vs. 30%), in T2 compared toT1 tumours (30% vs. 53.84%), in grade III versus grade I and II tumours (38.46 vs. 33.33%), in hormone receptor-positive than in receptor- negative tumours (41.9 vs. 0%) and in Ki67 ≤ 20% compared to Ki67 > 20% tumours (50% vs. 18.18%). None of these differences were statistically significant. Conclusion If we had applied the criteria of the Z0011 study, 39.3% of patients would have had residual disease. This seems to occur more frequently in patients 50 years or younger, with tumours larger than 2 cm, with high histological grade tumours, with positive hormone receptor and low Ki67. However, the low number of cases in our series does not allow definitive conclusions to be made.
- Axillary lymph node dissection
- Sentinel nodes