Vulvar angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma: An immunohistochemical and ultrastructural study

Francesc Alameda, Assumpció Munné, Teresa Baró, Mar Iglesias, Enric Condom, Josep Lloreta-Trull, Sergi Serrano

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16 Citations (Scopus)

Abstract

To investigate the histogenetical unifying theory of a single, pluripotential primitive cell for vulvar angiomyxoma, aggresive angiomyxoma, and angiomyofibroblastoma, an optical, immunohistochemical and ultrastructural study of a superficial angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma was performed. These three tumors showed immunohistochemical and ultrastructural overlapping features. The results of the study suggest that these three tumor entities probably arise on a common pluripotential primitive cell located around the vessels of connective tissue, which could show the capacity for modulating its penotype toward similar but distinct mature cell types. Copyright © Taylor & Francis Group, LLC.
Original languageEnglish
Pages (from-to)193-205
JournalUltrastructural Pathology
Volume30
Issue number3
DOIs
Publication statusPublished - 1 Jul 2006

Keywords

  • Aggressive angiomyxoma
  • Angiomyoblastoma
  • Angiomyxoma
  • Myofibroblast
  • Pericyte
  • Vulvar tumors

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