Abstract
It has been suggested that antioxidant administration to rats would reduce the physiological response to stress. In the present experiment adult male rats were given diets supplemented with vitamin E for one or seven days before they were subjected to immobilization stress. Vitamin E administration reduced hepatic and gastric lipid peroxidation in unstressed rats but did not modify the pituitary-adrenal, glucose and lactose responses to I or 18 h immobilization. Similarly, gastric ulceration caused by 18 h immobilization was unaffected by the diets. These results indicate that the inhibition of lipid peroxidation does not modify the response of several, well-known, stress-markers in the rat. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
Original language | English |
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Pages (from-to) | 113-118 |
Journal | Free Radical Research |
Volume | 9 |
DOIs | |
Publication status | Published - 1 Jan 1990 |
Keywords
- Free radicals
- Gastric ulceration
- Glucose
- Lactate
- Lipid peroxidation
- Pituitary-adrenal axis
- Stress
- Vitamin E