Vitamin e-supplemented diets reduce lipid peroxidation but do not alter either pituitary-adrenal, glucose, and lactate responses to immobilization stress or gastric ulceration

Antonio Armario, Lluis Campmany, Marta Borras, Juan Hidalgo

    Research output: Contribution to journalArticleResearchpeer-review

    27 Citations (Scopus)

    Abstract

    It has been suggested that antioxidant administration to rats would reduce the physiological response to stress. In the present experiment adult male rats were given diets supplemented with vitamin E for one or seven days before they were subjected to immobilization stress. Vitamin E administration reduced hepatic and gastric lipid peroxidation in unstressed rats but did not modify the pituitary-adrenal, glucose and lactose responses to I or 18 h immobilization. Similarly, gastric ulceration caused by 18 h immobilization was unaffected by the diets. These results indicate that the inhibition of lipid peroxidation does not modify the response of several, well-known, stress-markers in the rat. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
    Original languageEnglish
    Pages (from-to)113-118
    JournalFree Radical Research
    Volume9
    DOIs
    Publication statusPublished - 1 Jan 1990

    Keywords

    • Free radicals
    • Gastric ulceration
    • Glucose
    • Lactate
    • Lipid peroxidation
    • Pituitary-adrenal axis
    • Stress
    • Vitamin E

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