VCF2Networks: Applying genotype networks to single-nucleotide variants data

Giovanni Marco Dall'Olio, Ali R. Vahdati, Jaume Bertranpetit, Andreas Wagner, Hafid Laayouni

    Research output: Contribution to journalArticleResearchpeer-review

    1 Citation (Scopus)

    Abstract

    © The Author 2014. Published by Oxford University Press. All rights reserved. A wealth of large-scale genome sequencing projects opens the doors to new approaches to study the relationship between genotype and phenotype. One such opportunity is the possibility to apply genotype networks analysis to population genetics data. Genotype networks are a representation of the set of genotypes associated with a single phenotype, and they allow one to estimate properties such as the robustness of the phenotype to mutations, and the ability of its associated genotypes to evolve new adaptations. So far, though, genotype networks analysis has rarely been applied to population genetics data. To help fill this gap, here we present VCF2Networks, a tool to determine and study genotype network structure from single-nucleotide variant data.
    Original languageEnglish
    Pages (from-to)438-439
    JournalBioinformatics
    Volume31
    Issue number3
    DOIs
    Publication statusPublished - 15 Jul 2015

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