TY - JOUR
T1 - Validation of the Spanish version of Addenbrooke's Cognitive Examination III for diagnosing dementia
AU - Matias-Guiu, J. A.
AU - Fernández de Bobadilla, R.
AU - Escudero, G.
AU - Pérez-Pérez, J.
AU - Cortés, A.
AU - Morenas-Rodríguez, E.
AU - Valles-Salgado, M.
AU - Moreno-Ramos, T.
AU - Kulisevsky, J.
AU - Matías-Guiu, J.
PY - 2015/1/1
Y1 - 2015/1/1
N2 - © 2014 Sociedad Española de Neurología. Introduction: Addenbrooke's Cognitive Examination is a screening test used to diagnose dementia. The third edition of this test (ACE-III) was recently developed. The aim of this study was to translate and validate the ACE-III in Spanish. Methods: The ACE-III was translated and adapted to Spanish. It was then administered to a group of healthy subjects as well as a group of patients with different types of mild dementia treated in 2 hospitals in Spain. Results: Internal reliability (Cronbach's alpha = 0.927), inter-rater reliability (intraclass correlation coefficient = 0.976) and test-retest reliability (kappa 0.995) were excellent. Age (r = -0.512) and education (r = 0.659) showed a significant correlation with total test scores. The diagnostic accuracy of ACE-III was higher than that of the Mini-Mental State Examination, particularly for the group with the highest educational level. Researchers obtained normative data and cut-off points for the diagnosis of dementia. Conclusions: The Spanish version of the ACE-III is a reliable and valid test for diagnosing dementia. Its diagnostic accuracy is high, especially in patients with a higher level of education.
AB - © 2014 Sociedad Española de Neurología. Introduction: Addenbrooke's Cognitive Examination is a screening test used to diagnose dementia. The third edition of this test (ACE-III) was recently developed. The aim of this study was to translate and validate the ACE-III in Spanish. Methods: The ACE-III was translated and adapted to Spanish. It was then administered to a group of healthy subjects as well as a group of patients with different types of mild dementia treated in 2 hospitals in Spain. Results: Internal reliability (Cronbach's alpha = 0.927), inter-rater reliability (intraclass correlation coefficient = 0.976) and test-retest reliability (kappa 0.995) were excellent. Age (r = -0.512) and education (r = 0.659) showed a significant correlation with total test scores. The diagnostic accuracy of ACE-III was higher than that of the Mini-Mental State Examination, particularly for the group with the highest educational level. Researchers obtained normative data and cut-off points for the diagnosis of dementia. Conclusions: The Spanish version of the ACE-III is a reliable and valid test for diagnosing dementia. Its diagnostic accuracy is high, especially in patients with a higher level of education.
KW - Addenbrooke's Cognitive Examination
KW - Alzheimer disease
KW - Cognitive screening
KW - Dementia
KW - Frontotemporal dementia
KW - Neuropsychological assessment
U2 - 10.1016/j.nrl.2014.05.004
DO - 10.1016/j.nrl.2014.05.004
M3 - Article
SN - 0213-4853
VL - 30
SP - 545
EP - 551
JO - Neurologia
JF - Neurologia
IS - 9
ER -