Validation of numerical flow simulations against in vitro phantom measurements in different type B aortic dissection scenarios

Eduardo Soudah, Paula Rudenick, Maurizio Bordone, Bart Bijnens, David García-Dorado, Arturo Evangelista, Eugenio Oñate

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Abstract

© 2013 Taylor & Francis. An aortic dissection (AD) is a serious condition defined by the splitting of the arterial wall, thus generating a secondary lumen [the false lumen (FL)]. Its management, treatment and follow-up are clinical challenges due to the progressive aortic dilatation and potentially severe complications during follow-up. It is well known that the direction and rate of dilatation of the artery wall depend on haemodynamic parameters such as the local velocity profiles, intra-luminal pressures and resultant wall stresses. These factors act on the FL and true lumen, triggering remodelling and clinical worsening. In this study, we aimed to validate a computational fluid dynamic (CFD) tool for the haemodynamic characterisation of chronic (type B) ADs. We validated the numerical results, for several dissection geometries, with experimental data obtained from a previous in vitro study performed on idealised dissected physical models. We found a good correlation between CFD simulations and experimental measurements as long as the tear size was large enough so that the effect of the wall compliance was negligible.
Original languageEnglish
Pages (from-to)805-815
JournalComputer Methods in Biomechanics and Biomedical Engineering
Volume18
Issue number8
DOIs
Publication statusPublished - 11 Jun 2015

Keywords

  • aortic diseases
  • aortic dissection
  • computational fluid dynamics
  • in vitro phantoms

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