Usefulness of urinary antigen detection by an immunochromatographic test for diagnosis of pneumococcal pneumonia in children

J. Domínguez, S. Blanco, C. Rodrigo, M. Azuaray, N. Galí, A. Mainou, A. Esteve, A. Castellví, C. Prat, L. Matas, V. Ausina

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76 Citations (Scopus)

Abstract

We evaluated an immunochromatographic assay detecting pneumococcal antigen in urine samples from children diagnosed with pneumococcal pneumonia. The sensitivity and specificity of the immunochromatographic test with nonconcentrated urine (NCU) were 86.7 and 62.9%, respectively; with concentrated urine (CU), they were 100 and 11.7%, respectively. Pneumococcal antigen was also detected in 42.5% of NCU and 87.1% of CU samples from nasopharyngeal carriers. This is a nonspecific test for the diagnosis of pneumococcal pneumonia in children, particularly the very young.
Original languageEnglish
Pages (from-to)2161-2163
JournalJournal of Clinical Microbiology
Volume41
Issue number5
DOIs
Publication statusPublished - 1 May 2003

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