Usefulness of Proton Magnetic Resonance Spectroscopy in the Clinical Management of Brain Tumors

Research output: Chapter in BookChapterResearchpeer-review

1 Citation (Scopus)

Abstract

Single-voxel (SV) magnetic resonance spectroscopy (MRS) provides a noninvasive metabolic fingerprint for the multimodal evaluation and clinical management of brain tumoral masses thanks to the signals of protons from biomolecules such as lactate, lipids, creatine, or choline. This chapter considers three distinct scenarios in which SV MRS may be of clinical utility. First, when an abnormal mass is found in the brain, SV MRS can help in the differentiation between tumor and pseudotumoral pathology. Second, when the mass has been identified as a tumor, SV MRS can be of help in suggesting a specific diagnosis before a tumor sample can be analyzed by the pathologist. Finally, after treatment, SV MRS can be of help in assessing new lesions, by distinguishing between tumor progression and post-treatment changes. This chapter discusses the role of SV MRS in each one of these situations from a clinical point of view. © 2014 Elsevier Inc. All rights reserved.
Original languageEnglish
Title of host publicationMagnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications
Place of PublicationLondres (GB)
Pages141-161
Number of pages20
Edition1
DOIs
Publication statusPublished - 1 Dec 2013

Keywords

  • Abnormal brain mass
  • Choline
  • Glioblastoma
  • Mobile lipid
  • Pattern recognition
  • SV MRS

Fingerprint Dive into the research topics of 'Usefulness of Proton Magnetic Resonance Spectroscopy in the Clinical Management of Brain Tumors'. Together they form a unique fingerprint.

Cite this