Usefulness of an intraoperative electrophysiological navigator system for subthalamic nucleus surgery in Parkinson's disease

Alexandre Gironell, Gerard Amirian, Jaume Kulisevsky, Joan Molet

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Objects: The characteristics and benefits are presented of an intraoperative neurophysiological navigator computerized system developed in our center (Columbus-Track 1.0) that helps the surgical team in neuronal identification and in strategy processes in subthalamic nucleus surgery for Parkinson's disease (PD). Methods: The navigator consists of three assembled parts: (1) neuronal identification, based on wavelet processing, filtering and gaussian characteristics of the signal; (2) track identification, based on anatomical coincidence, somatomotor response and microstimulation quotient, and (3) strategy, coordinating correction for the next track. A retrospective comparative study was performed with 15 consecutive PD patients (30 targets) operated without the system and the next 15 consecutive patients operated with the aid of the system. With the aid of the computerized navigation system, a significant reduction in the number of tracks was observed (t = -2.503, p = 0.0015), with a mean difference of 1.2 tracks per hemisphere. A non-significant reduction in the total intervention time was also observed, with a mean difference of 20 min per hemisphere (t = -1.418, p = 0.161). Conclusions: The intraoperative computerized navigation system can aid the surgical team in better identifying the neuronal signal and in defining the optimal track to achieve the target. Copyright © 2005 S. Karger AG.
Original languageEnglish
Pages (from-to)101-107
JournalStereotactic and Functional Neurosurgery
Volume83
DOIs
Publication statusPublished - 1 Dec 2005

Keywords

  • Functional surgery
  • Microrecording
  • Parkinson's disease
  • Subthalamus

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