TY - JOUR
T1 - Use of interferon-gamma release assays to calculate the annual risk of tuberculosis infection
AU - Díez, Nuria
AU - Giner, Empar
AU - Latorre, Irene
AU - Lacoma, Alícia
AU - Roig, Francisco Javier
AU - Mialdea, Irene
AU - Díaz, Jessica
AU - Serra-Vidal, Mar
AU - Escribano, Amparo
AU - Domínguez, Jose
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Copyright © 2014 by Wolters Kluwer Health, Inc. All rights reserved. The objective was to assess the annual risk of tuberculosis infection by means of tuberculin skin testing (TST) in children, evaluating whether QuantiFERON-TB Gold In-Tube (QFN-G-IT) could improve the accuracy. On the basis of the positive TST results, the global annual incidence was estimated at 0.78%, with an increase in the prevalence from 0.64% to 1.68% in 2 years. However, QFN-G-IT was only positive in 6 of the 25 children with positive TST. The confirmation of the positive TST results by QFN-G-IT provided more accurate annual incidence estimation.
AB - Copyright © 2014 by Wolters Kluwer Health, Inc. All rights reserved. The objective was to assess the annual risk of tuberculosis infection by means of tuberculin skin testing (TST) in children, evaluating whether QuantiFERON-TB Gold In-Tube (QFN-G-IT) could improve the accuracy. On the basis of the positive TST results, the global annual incidence was estimated at 0.78%, with an increase in the prevalence from 0.64% to 1.68% in 2 years. However, QFN-G-IT was only positive in 6 of the 25 children with positive TST. The confirmation of the positive TST results by QFN-G-IT provided more accurate annual incidence estimation.
KW - Annual risk of tuberculosis infection
KW - QFN
KW - Tuberculin skin tests
U2 - 10.1097/INF.0000000000000514
DO - 10.1097/INF.0000000000000514
M3 - Article
VL - 34
SP - 219
EP - 221
JO - Journal of Pediatric Infectious Diseases
JF - Journal of Pediatric Infectious Diseases
SN - 1871-0336
IS - 2
ER -
