Use of interferon-gamma release assays to calculate the annual risk of tuberculosis infection

Nuria Díez; Empar Giner; Irene Latorre; Alícia Lacoma; Francisco Javier Roig; Irene Mialdea; Jessica Díaz; Mar Serra-Vidal; Amparo Escribano; Jose Domínguez

doi:10.1097/INF.0000000000000514

Use of interferon-gamma release assays to calculate the annual risk of tuberculosis infection

Nuria Díez, Empar Giner, Irene Latorre, Alícia Lacoma, Francisco Javier Roig, Irene Mialdea, Jessica Díaz, Mar Serra-Vidal, Amparo Escribano, Jose Domínguez

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

Copyright © 2014 by Wolters Kluwer Health, Inc. All rights reserved. The objective was to assess the annual risk of tuberculosis infection by means of tuberculin skin testing (TST) in children, evaluating whether QuantiFERON-TB Gold In-Tube (QFN-G-IT) could improve the accuracy. On the basis of the positive TST results, the global annual incidence was estimated at 0.78%, with an increase in the prevalence from 0.64% to 1.68% in 2 years. However, QFN-G-IT was only positive in 6 of the 25 children with positive TST. The confirmation of the positive TST results by QFN-G-IT provided more accurate annual incidence estimation.

Original language	English
Pages (from-to)	219-221
Journal	Journal of Pediatric Infectious Diseases
Volume	34
Issue number	2
DOIs	https://doi.org/10.1097/INF.0000000000000514
Publication status	Published - 1 Jan 2015

Keywords

Annual risk of tuberculosis infection
QFN
Tuberculin skin tests

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title = "Use of interferon-gamma release assays to calculate the annual risk of tuberculosis infection",

abstract = "Copyright {\textcopyright} 2014 by Wolters Kluwer Health, Inc. All rights reserved. The objective was to assess the annual risk of tuberculosis infection by means of tuberculin skin testing (TST) in children, evaluating whether QuantiFERON-TB Gold In-Tube (QFN-G-IT) could improve the accuracy. On the basis of the positive TST results, the global annual incidence was estimated at 0.78%, with an increase in the prevalence from 0.64% to 1.68% in 2 years. However, QFN-G-IT was only positive in 6 of the 25 children with positive TST. The confirmation of the positive TST results by QFN-G-IT provided more accurate annual incidence estimation.",

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Use of interferon-gamma release assays to calculate the annual risk of tuberculosis infection. / Díez, Nuria; Giner, Empar; Latorre, Irene; Lacoma, Alícia; Roig, Francisco Javier; Mialdea, Irene; Díaz, Jessica; Serra-Vidal, Mar; Escribano, Amparo; Domínguez, Jose.

In: Journal of Pediatric Infectious Diseases, Vol. 34, No. 2, 01.01.2015, p. 219-221.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Díez, Nuria

AU - Giner, Empar

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AU - Mialdea, Irene

AU - Díaz, Jessica

AU - Serra-Vidal, Mar

AU - Escribano, Amparo

AU - Domínguez, Jose

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