Up-to-date approach to manage keloids and hypertrophic scars: A useful guide

Anna I. Arno, Gerd G. Gauglitz, Juan P. Barret, Marc G. Jeschke*

*Corresponding author for this work

Research output: Contribution to journalReview articleResearchpeer-review

190 Citations (Scopus)


Keloids and hypertrophic scars occur anywhere from 30 to 90% of patients, and are characterized by pathologically excessive dermal fibrosis and aberrant wound healing. Both entities have different clinical and histochemical characteristics, and unfortunately still represent a great challenge for clinicians due to lack of efficacious treatments. Current advances in molecular biology and genetics reveal new preventive and therapeutical options which represent a hope to manage this highly prevalent, chronic and disabling problem, with long-term beneficial outcomes and improvement of quality of life. While we wait for these translational clinical products to be marketed, however, it is imperative to know the basics of the currently existing wide array of strategies to deal with excessive scars: from the classical corticotherapy, to the most recent botulinum toxin and lasers. The main aim of this review paper is to offer a useful up-to-date guideline to prevent and treat keloids and hypertrophic scars.

Original languageAmerican English
Pages (from-to)1255-1266
Number of pages12
Issue number7
Publication statusPublished - 1 Nov 2014


  • Corticoids
  • Criotherapy
  • Keloid
  • Laser
  • Review
  • Scar


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