Undifferentiated Wing Sarcoma in a Peach-Faced Lovebird (Agapornis roseicollis)

Irene Ruano-Feo, Bernat Martí-García, Oriol Jornet-Rius, Jaume Martorell*, Antonio Ramis

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review


A 10-year-old peach-faced lovebird (Agapornis roseicollis) was evaluated for an ulcerated and painful mass at the location of a fracture 2 years previously. Whole body radiographs showed a humeral fracture with a presumptive neoplastic proliferation in the distal diaphysis. Right wing amputation was elected but the animal died during recovery from surgery. Histopathological examination of the amputated wing revealed an infiltrative sarcomatous neoplastic proliferation. Immunohistochemistry (IHC) was carried out to characterize the tumour using antibodies against vimentin, desmin, smooth muscle actin (SMA), S-100, ionized calcium-binding adapter molecule-1 (IBA-1), CD18, cytokeratin and epithelial membrane antigen (EMA). The mesenchymal component of the mass was immunolabelled for vimentin and SMA and sparse epithelial cells were immunopositive for cytokeratin. Very few scattered cells were immunopositive for CD18 and IBA-1. The final diagnosis was consistent with an undifferentiated sarcoma with intralesional hyperplastic epithelium. According to the location, the history of a previous fracture and the histological pattern and IHC profile, the tumour was classified as an undifferentiated sarcoma with entrapped air sac epithelium.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalJournal of Comparative Pathology
Publication statusPublished - 1 Nov 2022


  • biphasic pattern
  • immunohistochemistry
  • lovebird
  • undifferentiated sarcoma


Dive into the research topics of 'Undifferentiated Wing Sarcoma in a Peach-Faced Lovebird (Agapornis roseicollis)'. Together they form a unique fingerprint.

Cite this