Tumors of the thyroid gland. Proposal for the management and study of samples from patients with thyroid neoplasms

José Manuel Cameselle-Teijeiro, María Rosa Bella Cueto, Catarina Eloy, Ihab Abdulkader, Isabel Amendoeira, Xavier Matías-Guiu, Manuel Sobrinho-Simões

Research output: Contribution to journalReview articleResearchpeer-review

Abstract

© 2019 Sociedad Española de Anatomía Patológica The recent changes in the classification and staging of thyroid tumors have arisen from the need to provide an adequate response to the exponential increase of thyroid cancer, which, however, has not been accompanied by an increase in mortality. These changes pretend to reduce overdiagnoses of malignancy, unnecessary treatment, side effects as well as cost for the health system. To this end, this article reviews recommendations for the management of thyroid surgical pathology samples with emphasis on the new terminology of the WHO classification. The basic criteria for the diagnosis of malignancy in well-differentiated thyroid carcinomas are reviewed and the criteria for NIFTP (non-invasive follicular tumor with papillary-like nuclear features) diagnosis are updated. Recommendations for the elaboration of the pathological report are also included.
Original languageEnglish
JournalRevista Espanola de Patologia
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Braf
  • Capsular invasion
  • Immunohistochemistry
  • Molecular pathology
  • Non-invasive follicular tumor with papillary-like nuclear features
  • RAS
  • TERT
  • Thyroid cancer
  • TP53
  • Vascular invasion

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