Treatment of pulmonary arterial hypertension

Antonio Roman, Manuel López-Meseguer, Enric Domingo

Research output: Contribution to journalReview articleResearchpeer-review

2 Citations (Scopus)


© 2014 Elsevier España, S.L.U. Treatment of pulmonary arterial hypertension has achieved significant progress over the past 20 years. Currently, 3 groups of drugs have proven useful for the treatment of this disease: endothelin receptor antagonist, phosphodiesterase inhibitors and prostacyclin and its analogues. It is recommended to initiate treatment with one of these drugs, the choice depending on the initial severity of patient disease and the preferences of the treating physician. When the patient does not have a satisfactory response, new drugs acting at a different pathway are most commonly added. At this time, considering referral for lung transplantation could be an alternative. Most experts recommend grouping maximum experience in what is known as expert centers. Treatment has led to better survival in these patients, but there is still a long way to cure this life-threatening disease.
Original languageEnglish
Pages (from-to)566-570
JournalMedicina Clinica
Issue number12
Publication statusPublished - 22 Jun 2015


  • Lung transplantation
  • Pulmonary arterial hypertension
  • Pulmonary hypertension


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