Treatment of persistent and recurrent nasopharyngeal carcinoma by brachytherapy

F. Guedea; J. Sole; J. Craven-Bartle; M. Vega; T. Eudaldo

Treatment of persistent and recurrent nasopharyngeal carcinoma by brachytherapy

F. Guedea, J. Sole, J. Craven-Bartle, M. Vega, T. Eudaldo

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Thirteen patients with locally recurrent or persistent nasopharyngeal carcinoma were re-treated with intracavitary brachytherapy associated or not with external radiation therapy at the Hospital de la Santa creu i Sant Pau in Barcelona, Spain, from February 1984 to May 1992. Eleven patients presented recurrent nasopharyngeal carcinoma and two patients presented with persistent nasopharyngeal carcinoma. Eight of the 13 patients (61%) were disease-free at 6, 6, 6, 8, 12, 20, 33 and 44 months after re-treatment; three of eight died of intercurrent disease at 6, 8, and 20 months. Five patients developed local recurrence and died at 14, 16, 28, 34 and 58 months after re-treatment. None of the patients experienced a significant complication of re-irradiation.

Original language	English
Pages (from-to)	223-227
Journal	Bulletin du Cancer/Radiotherapie
Volume	80
Issue number	3
Publication status	Published - 1 Jan 1993

Keywords

Brachytherapy
Nasopharyngeal carcinoma
Re-irradiation
Recurrence

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abstract = "Thirteen patients with locally recurrent or persistent nasopharyngeal carcinoma were re-treated with intracavitary brachytherapy associated or not with external radiation therapy at the Hospital de la Santa creu i Sant Pau in Barcelona, Spain, from February 1984 to May 1992. Eleven patients presented recurrent nasopharyngeal carcinoma and two patients presented with persistent nasopharyngeal carcinoma. Eight of the 13 patients (61%) were disease-free at 6, 6, 6, 8, 12, 20, 33 and 44 months after re-treatment; three of eight died of intercurrent disease at 6, 8, and 20 months. Five patients developed local recurrence and died at 14, 16, 28, 34 and 58 months after re-treatment. None of the patients experienced a significant complication of re-irradiation.",

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TY - JOUR

T1 - Treatment of persistent and recurrent nasopharyngeal carcinoma by brachytherapy

AU - Guedea, F.

AU - Sole, J.

AU - Craven-Bartle, J.

AU - Vega, M.

AU - Eudaldo, T.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Thirteen patients with locally recurrent or persistent nasopharyngeal carcinoma were re-treated with intracavitary brachytherapy associated or not with external radiation therapy at the Hospital de la Santa creu i Sant Pau in Barcelona, Spain, from February 1984 to May 1992. Eleven patients presented recurrent nasopharyngeal carcinoma and two patients presented with persistent nasopharyngeal carcinoma. Eight of the 13 patients (61%) were disease-free at 6, 6, 6, 8, 12, 20, 33 and 44 months after re-treatment; three of eight died of intercurrent disease at 6, 8, and 20 months. Five patients developed local recurrence and died at 14, 16, 28, 34 and 58 months after re-treatment. None of the patients experienced a significant complication of re-irradiation.

AB - Thirteen patients with locally recurrent or persistent nasopharyngeal carcinoma were re-treated with intracavitary brachytherapy associated or not with external radiation therapy at the Hospital de la Santa creu i Sant Pau in Barcelona, Spain, from February 1984 to May 1992. Eleven patients presented recurrent nasopharyngeal carcinoma and two patients presented with persistent nasopharyngeal carcinoma. Eight of the 13 patients (61%) were disease-free at 6, 6, 6, 8, 12, 20, 33 and 44 months after re-treatment; three of eight died of intercurrent disease at 6, 8, and 20 months. Five patients developed local recurrence and died at 14, 16, 28, 34 and 58 months after re-treatment. None of the patients experienced a significant complication of re-irradiation.

KW - Brachytherapy

KW - Nasopharyngeal carcinoma

KW - Re-irradiation

KW - Recurrence

M3 - Article

VL - 80

SP - 223

EP - 227

IS - 3

ER -