Towards perfect NMR: Spin-echo versus perfect-echo building blocks

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    © 2018 John Wiley & Sons, Ltd. The development of new tools to improve the quality of nuclear magnetic resonance (NMR) spectra is a challenging task. The concept of “perfect NMR” includes the design of robust pulse sequences that allow an investigator to obtain undistorted pure in-phase signals, with pure absorption lineshapes that are free of phase anomalies derived from undesired J modulations. Here, alternative NMR building blocks to the spin-echo that are based on a general double SE module, known as a perfect-echo, are reviewed. Several implementations to minimize/remove unwanted dispersive contributions in homonuclear and heteronuclear NMR experiments are described and illustrated with some examples of broad interest for small molecules.
    Original languageEnglish
    Pages (from-to)13-29
    JournalMagnetic Resonance in Chemistry
    Issue number1
    Publication statusPublished - 1 Jan 2019


    • NMR building blocks
    • NMR pulse sequence design
    • perfect BIRD
    • perfect INEPT
    • perfect spin-echo
    • perfect WATERGATE
    • perfect-echo
    • spin-echo


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