Toward the clinical use of circulating biomarkers predictive of bone union

Daniel Chaverri; Joaquim Vives

doi:10.2217/bmm-2017-0180

Toward the clinical use of circulating biomarkers predictive of bone union

Daniel Chaverri, Joaquim Vives

Research output: Contribution to journal › Review article › Research › peer-review

2 Citations (Scopus)

Abstract

© 2017 2017 Future Medicine Ltd. Current methods for diagnosis of bone healing after treatment of trauma injuries rely on clinical findings and the use of imaging methodologies that provide conclusive results but only at mid/long-term post-intervention. In this Perspective we present and discuss incipient evidence on biomarkers that may serve for monitoring the progression of bone healing as well as predicting eventual nonunion outcomes.

Original language	English
Pages (from-to)	1125-1133
Journal	Biomarkers in Medicine
Volume	11
Issue number	12
DOIs	https://doi.org/10.2217/bmm-2017-0180
Publication status	Published - 1 Dec 2017

Keywords

biomarker
nonunion
osteogenesis
pseudoarthrosis
regenerative medicine
TGF-β1

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10.2217/bmm-2017-0180

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title = "Toward the clinical use of circulating biomarkers predictive of bone union",

abstract = "{\textcopyright} 2017 2017 Future Medicine Ltd. Current methods for diagnosis of bone healing after treatment of trauma injuries rely on clinical findings and the use of imaging methodologies that provide conclusive results but only at mid/long-term post-intervention. In this Perspective we present and discuss incipient evidence on biomarkers that may serve for monitoring the progression of bone healing as well as predicting eventual nonunion outcomes.",

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AB - © 2017 2017 Future Medicine Ltd. Current methods for diagnosis of bone healing after treatment of trauma injuries rely on clinical findings and the use of imaging methodologies that provide conclusive results but only at mid/long-term post-intervention. In this Perspective we present and discuss incipient evidence on biomarkers that may serve for monitoring the progression of bone healing as well as predicting eventual nonunion outcomes.

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KW - osteogenesis

KW - pseudoarthrosis

KW - regenerative medicine

KW - TGF-β1

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JO - Biomarkers in Medicine

JF - Biomarkers in Medicine

SN - 1752-0363

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Toward the clinical use of circulating biomarkers predictive of bone union

Abstract

Keywords

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