© 2011, Pacini Editore S.p.A. All rights reserved. The aim of this study was to comprehensively describe the clinical comorbidities, concomitant treatments and the current therapeutic management of opiate-dependent patients undergoing a replacement therapy programme (RTP). This is an observational, cross-sectional, multicentre, epidemiological study conducted in 74 healthcare centres for drug users. Patients were diagnosed with Opiate Dependence (OD), and enrolled in a RTP in Spain (N=624). Most patients were men (84%); they received methadone (94%) at a mean dose of 61.52mg/day during the maintenance phase, orally (95%) with take-home doses (76%). High rates of infectious (59%) and psychiatric comorbidities (67%) were found. Patients infected by HIV, HCV or coinfected by HIV/HCV were given significantly higher methadone doses (p<0.0001).
|Journal||Heroin Addiction and Related Clinical Problems|
|Publication status||Published - 1 Sep 2011|
- Infectious comorbidites
- Opiate dependence
- Psychiatric comorbidities
- Replacement therapies
- Therapeutic management