Theophylline reverses haloperidol-induced catalepsy in the rat possible relevance to the pharmacological treatment of psychosis

Miquel Casas, Sergi Ferre, Teresa Guix, Francesc Jane

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Abstract

The effect of theophylline (5, 15, or 30 mg/kg sc) on the catalepsy induced by haloperidol in the rat was studied. Theophylline was shown to induce a dose-dependent inhibition of this catalepsy. These data support the hypothesis that the methylxanthines are dopamine agonists and suggest that coffee, tea, and cola drinks should be avoided by patients undergoing neuroleptic treatment. © 1988.
Original languageEnglish
Pages (from-to)642-648
JournalBiological Psychiatry
Volume24
Issue number6
DOIs
Publication statusPublished - 1 Jan 1988

Fingerprint Dive into the research topics of 'Theophylline reverses haloperidol-induced catalepsy in the rat possible relevance to the pharmacological treatment of psychosis'. Together they form a unique fingerprint.

Cite this