The Search for Biochemical Photoprobes. III. The Photoreactions of 4-Nitroveratrole and 2-Fluoro-4-nitroanisole with Bovine Pancreatic Ribonuclease A and with Model Nucleophiles.

Jorge Marquet, Lourdes Rafecas, Albert Cantos, Marcial Moreno-Mañas, Maria Cervera, Francisco Casado, M. Victòria Nogués, Claudi M. Cuchillo

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7 Citations (Scopus)

Abstract

The photoreactions of 4-nitroveratrole (NVT) and 2-fluoro-4-nitroanisole (FNA) with bovine pancreatic ribonuclease A (RNAase A) and with model nucleophiles are described. From them it is concluded that 2-fluoro-4-nitrophenyl ethers constitute improved alternative biochemical photoprobes, specially for proteins where a number of good nucleophiles are present. © 1993.
Original languageEnglish
Pages (from-to)1297-1306
JournalTetrahedron
Volume49
Issue number6
DOIs
Publication statusPublished - 5 Feb 1993

Keywords

  • Nitrophenyl Ethers
  • Photoprobes
  • Photosubstitution
  • Ribonuclease

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