The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced Aβ42 production mediated by familial early-onset Alzheimer's disease-linked PS variants

C.A. Saura, T. Tomita, M. Takahashi, J.Y. Leem, T. Iwatsubo T. Honda, G. Thinakaran

Research output: Contribution to journalArticleResearch

52 Citations (Scopus)
Original languageEnglish
Pages (from-to)17136-17142
JournalJournal of Biological Chemistry
Issue number22
Publication statusPublished - 1 Jan 2000

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