The neuropsychological phenotype of attention deficit hyperactivity disorder: are there differences among subtypes?

C. Capdevila-Brophy, J. Artigas-Pallarés, A. Ramirez-Mallafré, M. López-Rosendo, J. Real, J. E. Obiols-Llandrich

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Abstract

INTRODUCTION: Recent studies suggest that the ADHD subtypes would be best conceptualized as separate clinical entities, based on their epidemiology, central and associate symptomatology. OBJECTIVES: To determine the differences and similarities between subtypes in its associate symptomatology, specifically in the neuropsychological phenotype of executive dysfunction. PATIENTS AND METHODS: A group of children between 6 and 14 years of age with a diagnosis of ADHD-innattentive subtype (DESAT, n = 20) and another with ADHD-combined subtype (COMB, n = 39). RESULTS: Overall, the COMB subject sample displayed lower performance than DESAT group. Statistically significant differences were found in Kaufman-ABC-hands movement subtest, Wisconsin Card Sorting Test (WCST)-total error and WCST-conceptual level. CONCLUSIONS: The subtypes differ significantly in measures or non verbal working memory, hindsight, foresight, and motor control. Both groups share a deficit in response output speed and verbal working memory. We hypothesized areas of cognitive superiority for each subtype: spatial memory for the inattentive and gestaltic composition for the combined. Results provide evidence to support quantitative and qualitative differences in the neuropsychological profile between the ADHD-innatentive and combined subtypes.
Original languageEnglish
Pages (from-to)17-23
JournalRevista de neurologia
Volume40 Suppl 1
Issue number1
Publication statusPublished - 1 Jan 2005

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