The Leptospira interrogans lexA gene is not autoregulated

Jordi Cuñée, Paul Cullen, Gerard Mazon, Susana Campoy, Ben Adler, Jordi Barbe

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)


Footprinting and mutagenesis experiments demonstrated that Leptospira interrogans LexA binds the palindrome TTTGN5CAAA found in the recA promoter but not in the lexA promoter. In silico analysis revealed that none of the other canonical SOS genes is under direct control of LexA, making the leptospiral lexA gene the first described which is not autoregulated. Copyright © 2005, American Society for Microbiology. All Rights Reserved.
Original languageEnglish
Pages (from-to)5841-5845
JournalJournal of Bacteriology
Publication statusPublished - 1 Aug 2005


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