The intensive care medicine research agenda for airways, invasive and noninvasive mechanical ventilation

Samir Jaber, Giacomo Bellani, Lluis Blanch, Alexandre Demoule, Andrés Esteban, Luciano Gattinoni, Claude Guérin, Nicholas Hill, John G. Laffey, Salvatore Maurizio Maggiore, Jordi Mancebo, Paul H. Mayo, Jarrod M. Mosier, Paolo Navalesi, Michael Quintel, Jean Louis Vincent, John J. Marini

    Research output: Contribution to journalReview articleResearchpeer-review

    29 Citations (Scopus)


    © 2017, Springer-Verlag GmbH Germany and ESICM. In an important sense, support of the respiratory system has been a defining characteristic of intensive care since its inception. The pace of basic and clinical research in this field has escalated over the past two decades, resulting in palpable improvement at the bedside as measured by both efficacy and outcome. As in all medical research, however, novel ideas built upon observations are continually proposed, tested, and either retained or discarded on the basis of the persuasiveness of the evidence. What follows are concise descriptions of the current standards of management practice in respiratory support, the areas of present-day uncertainty, and our suggested agenda for the near future of research aimed at testing current assumptions, probing uncertainties, and solidifying the foundation on which to base our progress to the next level.
    Original languageEnglish
    Pages (from-to)1352-1365
    JournalIntensive Care Medicine
    Issue number9
    Publication statusPublished - 1 Sep 2017


    • Acute respiratory failure
    • Airways
    • Intubation
    • Mechanical ventilation
    • Non-invasive ventilation
    • Weaning


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