The design and synthesis of novel 3-[2-indol-1-yl-ethyl]-1H-indole derivatives as selective inhibitors of CDK4

Carine Aubry, Asma Patel, Sachin Mahale, Bhabatosh Chaudhuri, Jean Didier Maréchal, Michael J. Sutcliffe, Paul R. Jenkins*

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Abstract

We present the design, synthesis and biological activity of novel 3-[2-indol-1-yl-ethyl]-1H-indole selective inhibitors of CDK4.

Original languageEnglish
Pages (from-to)1423-1425
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number9
DOIs
Publication statusPublished - 28 Feb 2005

Keywords

  • 3-[2-Indol-1-yl-ethyl]-1H-indole
  • CDK4
  • Fascaplysin
  • IC
  • Indole
  • Molecular modelling

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