Paired samples of saliva and serum from 286 highrisk subjects were tested for HIV using two commercial enzyme immunoassays following the same WHO testing strategy supplemented with a Western blot technique. Agreement between HIV testing in both sample types was 98.9 % (95 % confidence interval: 97.7-100). The sensitivity of an EIA (Wellcozyme GACELISA) alone for saliva was 100% (133/133) and the specificity 98.7% (151/153). These results support previous data showing that in some situations saliva might be an effective alternative to serum for HIV testing. © 1995 Springer-Verlag.
|Journal||European Journal of Clinical Microbiology & Infectious Diseases|
|Publication status||Published - 1 Aug 1995|
Mayans, M. V., Casabona, J., Rabella, N., De Miniac, D., Rodés, A., Marco, A., Trabal, J., & Trilla, C. (1995). Testing of saliva and serum for HIV in high-risk populations. European Journal of Clinical Microbiology & Infectious Diseases, 14, 710-713. https://doi.org/10.1007/BF01690881